BDBM50000541 (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea::1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea::CHEMBL93::Leutrol::N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea::N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea::ZILEUTON::Zyflo (TN)
SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1
InChI Key InChIKey=MWLSOWXNZPKENC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50000541
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of FLAP in Ca+2 ionophore A23187 stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 1...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISAMore data for this Ligand-Target Pair